Hundreds of Quantum Applications

Employing D-Wave's annealing quantum computing solutions as accelerators in the speed and quality of training our generative AI-driven, drug discovery (DD) analysis systems, we constructed a hybrid quantum and classical computer system, aiming to extend the applicable range of molecular-generation AI systems in the DD field (i.e., AI-driven Drug Design). The goal of our project is to pioneer a new process for discovering 'first-in-class' pharmaceutical small compounds, which is performed with supports by D-Wave's team of professional services experts. In my talk, we report substantial aspects of our projects, based on the above-mentioned strategy and present progress.

Maintaining steady connections on a mobile network entails a lot of behind-the-scenes effort. Work done by Japanese telecommunications company NTT DOCOMO demonstrated that quantum computing can help mitigate potential performance issues on mobile networks during periods of heavy use. This is now an in-production application for NTT DOCOMO.

Supreeth Mysore Venkatesh, Antonio Macaluso, Marlon Nuske, Matthias Klusch, Andreas Dengel 

Deutsches Forschungszentrum für Künstliche

https://arxiv.org/abs/2408.06007

The increasing number of Low Earth Orbit (LEO) satellites, driven by lower manufacturing and launch costs, is proving invaluable for Earth observation missions and low-latency internet connectivity. However, as the number of satellites increases, the number of communication links to maintain also rises, making the management of this vast network increasingly challenging and highlighting the need for clustering satellites into efficient groups as a promising solution. This paper formulates the clustering of LEO satellites as a coalition structure generation (CSG) problem and leverages quantum annealing to solve it. We represent the satellite network as a graph and obtain the optimal partitions using a hybrid quantum-classical algorithm called GCS-Q. The algorithm follows a top-down approach by iteratively splitting the graph at each step using a quadratic unconstrained binary optimization (QUBO) formulation. To evaluate our approach, we utilize real-world three-line element set (TLE/3LE) data for Starlink satellites from Celestrak. Our experiments, conducted using the D-Wave Advantage annealer and the state-of-the-art solver Gurobi, demonstrate that the quantum annealer significantly outperforms classical methods in terms of runtime while maintaining the solution quality. The performance achieved with quantum annealers surpasses the capabilities of classical computers, highlighting the transformative potential of quantum computing in optimizing the management of large-scale satellite networks.

Abhishek Awasthi∗, Nico Kraus†, Florian Krellner‡, David Zambrano†

*BASF Digital Solutions GmbH, Ludwigshafen am Rhein, Germany

†Aqarios GmbH, Munich, Germany

‡SAP SE, Walldorf, Germany

This work is a benchmark study for quantum- classical computing method with a real-world optimization problem from industry. The problem involves scheduling and balancing jobs on different machines, with a non-linear objective function. We first present the motivation and the problem description, along with different modeling techniques for classical and quantum computing. The modeling for classical solvers has been done as a mixed-integer convex program, while for the quantum-classical solver we model the problem as a binary quadratic program, which is best suited to the D-Wave Leap’s Hybrid Solver. This ensures that all the solvers we use are fetched with dedicated and most suitable model(s). Henceforth, we carry out benchmarking and comparisons between classical and quantum-classical methods, on problem sizes ranging till approximately 150, 000 variables. We utilize an industry grade classical solver and compare its results with D-Wave Leap’s Hybrid Solver. The results we obtain from D-Wave are highly competitive and sometimes offer speedups, compared to the classical solver.

Supply Chain/ Logistics SavantX with videoQuantum Computing has shown how it can make a difference in optimizing logistics. SavantX developed the HONE (Hyper Optimized Nodal Efficiency) Engine, which uses proprietary data science and quantum computing to present real-time optimized solutions for use at the second largest container terminal at the Port of Los Angeles, Pier 300. SavantX leverages the D-Wave quantum computer repeatedly in transportation applications in real-time. Hear about lessons learned in applying quantum solutions to a real-world application and how quantum compares to the classical approach.

The future is quantum – this is precisely why NEC and CSIRO provided a breakdown of the importance of quantum. In this talk, NEC reveals its plans to drive higher sustained performance using D-Wave’s quantum technologies and how CSIRO is making leaps for solving material microstructure modeling with D-Wave Leap™.

Noisy intermediate-scale quantum (NISQ) hardware is almost universally incompatible with full-scale optimization problems of practical importance which can have many variables and unwieldy objective functions. As a consequence, there is a growing body of literature that tests quantum algorithms on miniaturized versions of problems that arise in an operations research setting. Rather than taking this approach, we investigate a problem of substantial commercial value, multi-truck vehicle routing for supply chain logistics, at the scale used by a corporation in their operations. Such a problem is too complex to be fully embedded on any near-term quantum hardware or simulator; we avoid confronting this challenge by taking a hybrid workflow approach: we iteratively assign routes for trucks by generating a new binary optimization problem instance one truck at a time. Each instance has ∼2500 quadratic binary variables, putting it in a range that is feasible for NISQ quantum computing, especially quantum annealing hardware. We test our methods using simulated annealing and the D-Wave Hybrid solver as a place-holder in wait of quantum hardware developments. After feeding the vehicle routes suggested by these runs into a highly realistic classical supply chain simulation, we find excellent performance for the full supply chain. Our work gives a set of techniques that can be adopted in contexts beyond vehicle routing to apply NISQ devices in a hybrid fashion to large-scale problems of commercial interest.

Optimizing package loading within trucks for manufacturers and distributors can result in cost and time savings. In this talk, Senior Manager Nitish Umang discusses his joint work with D-Wave and show a demo for the 3D cuboid loading problem. This is a good candidate for quantum optimization due to the combinatorial nature of the problem.

Quantum annealing is a promising approach for obtaining good approximate solutions to difficult optimization problems. Folding a protein sequence into its minimum-energy structure represents such a problem. For testing new algorithms and technologies for this task, the minimal lattice-based HP model is well suited, as it represents a considerable challenge despite its simplicity. The HP model has favorable interactions between adjacent, not directly bound hydrophobic residues. Here, we develop a novel spin representation for lattice protein folding tailored for quantum annealing. With a distributed encoding onto the lattice, it differs from earlier attempts to fold lattice proteins on quantum annealers, which were based upon chain growth techniques. With our encoding, the Hamiltonian by design has the quadratic structure required for calculations on an Ising-type annealer, without having to introduce any auxiliary spin variables. This property greatly facilitates the study of long chains. The approach is robust to changes in the parameters required to constrain the spin system to chain-like configurations, and performs very well in terms of solution quality. The results are evaluated against existing exact results for HP chains with up to N=30 beads with 100% hit rate, thereby also outperforming classical simulated annealing. In addition, the method allows us to recover the lowest known energies for N=48 and N=64 HP chains, with similar hit rates. These results are obtained by the commonly used hybrid quantum-classical approach. For pure quantum annealing, our method successfully folds an N=14 HP chain. The calculations were performed on a D-Wave Advantage quantum annealer.

Computed tomography (CT) is an important imaging technique used in medical analysis of the internal structure of the human body. Previously, image segmentation methods were required after acquiring reconstructed CT images to obtain segmented CT images which made it susceptible to errors from both reconstruction and segmentation algorithms. However, this paper introduces a new approach using an advanced quantum optimization algorithm called quadratic unconstrained binary optimization (QUBO). This algorithm enables acquisition of segmented CT images from X-ray projection data with minimized discrepancies between experimentally obtained sinograms and quantized sinograms derived from quantized segmented CT images using the Radon transform. This study utilized D-Wave's hybrid solver system for verification on real-world X-ray data.

In this paper an application of D-Wave Systems quantum annealer for optimizing initial line-up of a soccer team is presented. Players and their playing position are selected to maximize the sum of players ratings for both a 4-3-3 attack formation and a 4-2-3-1 medium defensive formation. The problem is stated as a binary quadratic model (BQM) and it is solved in a D-Wave Leap Hybrid Solver. Results are presented and compared with already published results obtained with a classical solver.